电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CXCR3 抗体

This anti-CXCR3 antibody is a 小鼠 单克隆 antibody detecting CXCR3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7673000
发货至: 中国

Quick Overview for CXCR3 抗体 (ABIN7673000)

抗原

See all CXCR3 抗体
CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

适用

  • 93
  • 55
  • 16
  • 1

宿主

  • 83
  • 22
  • 21
  • 1
  • 1
小鼠

克隆类型

  • 72
  • 56
单克隆

标记

  • 47
  • 13
  • 10
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CXCR3 antibody is un-conjugated

应用范围

  • 73
  • 65
  • 35
  • 35
  • 15
  • 15
  • 14
  • 13
  • 12
  • 11
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

6F7
  • 原理

    CXCR3-specific antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: peptide(N-terminal,extracellular domain)

    Immunogen: chemokine(C-X-C motif) receptor 3

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

    别名

    CXCR3

    背景

    Synonyms: C-X-C chemokine receptor type 3 (CXC-R3, CXCR-3)|CKR-L2|G protein-coupled receptor 9|Interferon-inducible protein 10 receptor (IP-10 receptor)|CXCR3|GPR9

    Background: CXCR3(C-X-C chemokine receptor type 3) is a G protein-coupled, seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+ and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells(PMID: 16847335). CXCR3 binds and is activated by the three IFN-gamma-inducible chemokines: CXCL9, CXCL10, and CXCL11. Binding of these ligands to CXCR3 has been implicated in regulating T-cell infiltration during inflammation and tissue injury(PMID: 17250586). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms, CXCR3B, mediates the angiostatic activity of CXCR3 ligands and also acts as functional receptor for CXCL4(PMID:12782716). This monoclonal antibody is specific to CXCR3B.

    分子量

    40 kDa+43 kDa

    基因ID

    2833

    UniProt

    P49682
You are here:
Chat with us!